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Oncology Medicines

Temozolomide Capsules – Tamodal 100 mg

Tamodal 100 mg (Temozolomide Capsules) is an oral chemotherapy medication used for the treatment of glioblastoma multiforme (GBM) and anaplastic astrocytoma. It works by damaging cancer cell DNA, thereby slowing or stopping tumor growth.

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Description

Tamodal 100 mg contains Temozolomide, an oral alkylating agent widely used in neuro-oncology. It is a standard component of treatment protocols for malignant brain tumors, often administered alongside radiotherapy or as maintenance therapy.

🔬 Mechanism of Action

Temozolomide is converted in the body to its active metabolite (MTIC), which methylates DNA at specific sites. As a result, it interferes with DNA replication and triggers cancer cell death. Therefore, it effectively targets rapidly dividing tumor cells in the brain.

💊 Indications

Tamodal 100 mg is indicated for:

  • Newly diagnosed Glioblastoma Multiforme (GBM) (in combination with radiotherapy, followed by maintenance therapy)
  • Recurrent or refractory Anaplastic Astrocytoma
  • Other malignant gliomas as prescribed by an oncologist

📌 Key Features of Tamodal 100 mg

  • Strength: 100 mg
  • Dosage Form: Oral capsule
  • Therapeutic Class: Alkylating Agent
  • Administration: Taken orally, dosing based on body surface area and treatment phase
  • Monitoring: Requires regular complete blood count (CBC) and liver function tests

⚕️ Benefits of Temozolomide

  • Oral chemotherapy for convenience
  • Standard-of-care therapy in GBM treatment
  • Effective in both concurrent and maintenance settings
  • Crosses the blood-brain barrier for targeted action

⚠️ Precautions

  • Risk of myelosuppression (neutropenia, thrombocytopenia)
  • Nausea, vomiting, fatigue, and constipation may occur
  • Risk of opportunistic infections in prolonged therapy
  • Regular blood monitoring required
  • Use strictly under oncologist supervision

Tamodal 100 mg (Temozolomide Capsules) is a key oral chemotherapy agent in the management of malignant brain tumors, offering effective disease control and improved survival outcomes when used as part of comprehensive neuro-oncology treatment protocols.

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