Description
Cytasted 1000 mg contains Cytarabine – Cytosine Arabinoside, Cytarabine Injection BP, a pyrimidine analog antimetabolite widely used in leukemia treatment protocols. It is administered intravenously or subcutaneously under strict medical supervision in oncology settings.
🔬 Mechanism of Action
Cytarabine is converted inside the body to its active metabolite (Ara-CTP), which inhibits DNA polymerase. As a result, it disrupts DNA synthesis during the S-phase of the cell cycle, leading to the death of rapidly dividing leukemia cells.
💊 Indications
Cytasted 1000 mg is indicated for:
- Acute Myeloid Leukemia (AML)
- Acute Lymphoblastic Leukemia (ALL)
- Chronic Myelogenous Leukemia (CML) blast crisis
- Non-Hodgkin Lymphoma (in selected regimens)
- Other hematologic malignancies as prescribed
It is commonly used in induction, consolidation, and high-dose chemotherapy regimens.
📌 Key Features of Cytasted 1000 mg
- Strength: 1000 mg
- Dosage Form: Injection (IV/Subcutaneous administration)
- Therapeutic Class: Antimetabolite Chemotherapy
- Administration: Given in hospital under oncology supervision
- Monitoring: Requires regular complete blood count (CBC), liver and kidney function monitoring
⚕️ Benefits of Cytarabine
- Essential component of leukemia treatment protocols
- Effective in induction and consolidation therapy
- High-dose regimens improve remission outcomes
- Targets rapidly dividing cancer cells
⚠️ Precautions
- Severe bone marrow suppression (neutropenia, thrombocytopenia)
- Risk of infections and bleeding
- Nausea, vomiting, mucositis, and neurotoxicity (especially in high doses)
- Requires strict monitoring during treatment
- Use strictly under hematologist/oncologist supervision
Cytasted 1000 mg (Cytarabine Injection BP) is a cornerstone chemotherapy agent in leukemia management, playing a critical role in induction and consolidation therapy for improved remission and survival outcomes.
