Description
Hertab 250 mg contains Lapatinib, a dual tyrosine kinase inhibitor that targets both HER2 (ErbB2) and EGFR (ErbB1) receptors. It is commonly used in patients with advanced or metastatic HER2-positive breast cancer, especially after progression on prior therapies.
🔬 Mechanism of Action
Lapatinib inhibits intracellular tyrosine kinase domains of HER2 and EGFR receptors. As a result, it:
- Blocks tumor cell signaling pathways
- Inhibits cancer cell proliferation
- Promotes apoptosis (cell death)
This dual inhibition helps control tumor growth in HER2-driven cancers.
💊 Indications
Hertab 250 mg is indicated for:
- HER2-positive advanced or metastatic breast cancer
- Often used in combination with capecitabine or letrozole depending on patient profile
- Patients who have received prior treatments including trastuzumab
📌 Key Features of Hertab 250 mg
- Strength: 250 mg
- Dosage Form: Oral tablet
- Therapeutic Class: Dual Tyrosine Kinase Inhibitor (HER2/EGFR)
- Administration: Taken orally once daily as prescribed
- Monitoring: Liver function tests and cardiac monitoring recommended
⚕️ Benefits of Lapatinib
- Targeted therapy for HER2-positive breast cancer
- Oral administration for convenience
- Effective in patients resistant to prior HER2 therapies
- Helps delay disease progression
⚠️ Precautions for Hertab 250 mg
- Risk of diarrhea, rash, and fatigue
- Potential hepatotoxicity
- Cardiac function monitoring required
- Drug interactions possible
- Use strictly under oncologist supervision
Hertab 250 mg (Lapatinib Tablets) provides an effective targeted treatment option for HER2-positive breast cancer, helping improve disease control and patient outcomes when used under specialized oncology care.




